Berkoff will direct the production, which features production design by Nigel Hook and lighting design by Mike Robertson.
In the play, six actors are on a movie set waiting for their call. Until then, they are in limbo needing the director to bring them to life.
Berkoff has directed, written, and appeared in numerous stage productions, including East, Decadence, The Secret Love Life Of Ophelia, Massage, and Acapulco, and has appeared in dozens of films.
For tickets and information, call 020-7907-7075 or visit www.charingcrosstheatre.co.uk.