With Hawke in the title role and Duff as Lady Macbeth, the company will also feature Richard Easton as Duncan, Brian d’Arcy James as Banquo, Jonny Orsini as Malcolm, Daniel Sunjata as Macduff, Bianca Amato as Lady Macduff, Malcolm Gets, John Glover, and Byron Jennings as the Three Witches, and an ensemble including Shirine Babb, John Patrick Doherty, Austin Durant, Francesca Faridany, Stephanie Fieger, Ben Horner, Ruy Iskandar, Aaron Krohn, Jeremiah Maestas, Christopher McHale, Sam Poon, Triney Sandoval, Nathan Stark, Patrick Vaill, Tyler Lansing Weaks, and Derek Wilson.
The creative team for Macbeth will include Scott Pask (scenic design), Catherine Zuber (costume design), Japhy Weideman (lighting design), Mark Bennett (original music and sound), Jeff Sugg (projections), and Steve Rankin (fights).