Miss Sherlock Holmes, possessor of one of the greatest deductive minds of her generation, finds herself regularly incarcerated for behaviors deemed abnormal in a “respectable” lady. Miss Dorothy Watson struggles to make a difference at the only hospital in England that will hire female doctors. These unconventional women, trapped in an era that refuses to accept them, must forge a bond of trust and work together to uncover the secrets surrounding a corrupt police investigator whose wives have a habit of turning up dead. A thrilling murder mystery that re-introduces familiar characters from the works of Sir Arthur Conan Doyle under a brand new light, in a world premiere production.