Most recently, Byrne was seen starring in Mary Bronstein’s If I Had Legs I’d Kick You for A24. Byrne garnered the Silver Bear for Best Leading Performance at the 2025 Berlin International Film Festival, a Gotham Award nomination, a Film Independent Spirit Award nomination, a Critics Choice nomination, an Actors Award nomination, and a Golden Globe Award in the category of ‘Best Performance by a Female Actor in a Motion Picture – Musical or Comedy’ for her performance.
Upcoming, Byrne is set to star in Stephanie Laing’s TOW.
Previously on television, Byrne starred in Damages opposite Glenn Close for which she garnered two Golden Globe nominations and one Emmy nomination for her portrayal. Her additional television credits include Physical, Platonic and Mrs. America.
It was recently announced that Byrne is set to star in Peacock series The Good Daughter.
Previous film credits include: Juliet, Naked; Peter Rabbit; Instant Family; Spy; The Place Beyond the Pines; Bridesmaids; Insidious; Get Him to the Greek; 28 Weeks Later; Bridesmaids; Marie Antionette; Troy; The Goddess of 1967 for which she garnered the Volpi Cup at the 2000 Venice Film Festival and Two Hands.
Her theatre credits include Medea, You Can’t Take it With You (Broadway debut), Sydney Theatre Company’s Speed-the-Plow, La Dispute, and Three Sisters.
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