Joining the previously announced Lynn Redgrave in the title role will be Philip Goodwin (Tony), Oscar Isaac (Tom), and K.K. Moggie (Ruth).
The show, which premiered in London, focuses on Grace, a noted scientist and avowed atheist, who turns against her son, Tom, a lawyer who plans to become a Christian minister.
Redgrave received Tony Award nominations for her work in The Constant Wife, Shakespeare for My Father (which she wrote), and Mrs. Warren's Profession. She won Obie and Drama Desk Awards for Talking Heads. Redgrave is also a two-time Oscar nominee for Georgy Girl and Gods and Monsters.