Tilly is a sad bank teller who turns her melancholy nature into something sexy, and every stranger she meets falls in love with her. One day Tilly becomes happy, which wreaks havoc on the lives of her lovers. Frances, a hairdresser, falls in love with her, and eventually becomes so melancholy that she turns into an almond. It’s up to Tilly to rescue her. In a world where one can become happy with the swallow of a pill, Melancholy Play takes a look at the traditions of happiness and sadness in America today.