Grace and Glorie is set in the Blue Ridge Mountains. Grace is an elderly cancer patient who has checked herself out of the hospital and returned to her beloved homestead cottage to die alone. Her reluctant caregiver, Glorie, is a New York City sophisticate who volunteers to be a hospice worker. The young urbanite and the cantankerous mountain dweller clash at first. Ultimately, the generation gap begins to narrow as both find joy and friendship from unexpected sources.