Among the other guest voices for the upcoming season are Michael Douglas, Tina Fey, Michael J. Fox, and Jamie Oliver. Douglas will guest alongisde his son Dylan in an episode that takes place in a haunted house, while Pacquin and Fox will pay homage to their True Blood and Teen Wolf characters. Lynch is set to play the mother of a boy that the title characters' sister is dating.
Vincent Martella, Thomas Sangster, Ashley Tisdale, Mitchel Musso, Caroline Rhea, Richard O'Brien, Dee Bradley Baker, Alyson Stoner and co-creators Jeff "Swampy" Marsh and Dan Povenmire comprise the series' regular cast.