Sex! Drugs! & Ukuleles! is set at the end of the 21st century, when the drug companies are finally in control of the world. Sex is illegal in this futuristic utopia, as is failure to take your drugs. So is making music, unless you're a member of the corporate Top 10. Three young outlaw musicians meet in secret to play their ukuleles, which is tantamount to musical sedition. They fall under the wing of a mysterious stranger with a secret to share, who guides them through the dangerous vicissitudes of a controlled society to the status of "chosen musical gods," after a series of comic twists and turns.