Christopher Randolph will direct the Origin Theatre Company mounting, featuring Irish Theatre Festival Award winner Carey Van Driest.
Horne's Birdland debut will include a preview of The Night Before My Wedding, a collaboration with Neil Gaiman.
Kathryn Erbe, Roxanna Hope, and Arliss Howard star in the production.
The one-night-only concert will play at 54 Below.
Clifton Oliver and Allison Semmes will portray the legendary Motown couple in performances across the country.
Plays by David Lindsay-Abaire and John Guare are on the docket to be performed for live audiences.
Irish tunes will be heard during the show's nightly pre-show concert.
A new play and musical will be presented at Saint Peter's Church.
The Jon Robin Baitz drama will begin performances April 10 off-Broadway.
Alan Golub and Laura Goldfader's musical will have had 16 performances by the end of its run.