Christopher Durang's comedy comes to life under the direction of Jessica Stone.
Jackson Gay directs the drama, which weaves together characters including Harriet Tubman and Timothy McVeigh.
David Greig's play features a full choir at every performance.
PigPen Theatre Co. and Benjamin Scheuer will also participate.
The new season will also see Jonathan Groff and Sutton Foster in acclaimed off-Broadway musicals.
The writer and performer takes on his musical once again, this time on Broadway, beginning January 21.
The comedy comes back to life off-Broadway.