The up-and-coming director and songwriter bring their large-scale theatrical pageant to Central Park's Delacorte Theater.
The cast will also include Christopher Fitzgerald, Isaiah Johnson, and David Turner.
New plays by Robert O'Hara and Heidi Schreck will kick off the season.
Plays by David Mamet, Todd Almond, and more will be featured during the mainstage season.
Scott expands her acclaimed solo show, Piece of Meat, for her newest musical venture.
The season's world premieres will also feature the work of Pulitzer Prize- and Tony Award-winning playwright Bruce Norris.
The new play is led by Jessica Hecht and Dominic Fumusa.
The event, which will take place at 54 Below, will also feature Lauren Molina, Todd Almond, and Amy Spanger.