Tony Award winner Julie Taymor will direct the show, which will feature music and lyrics by Bono and The Edge of U2, and a book by Taymor and Glen Berger. Evan Rachel Wood and Alan Cumming have previously been confirmed for the production as Mary Jane Watson and the Green Goblin, respectively. Additional casting is still to be announced.

The musical is based on the Marvel Comics character, and follows the story of teenager Peter Parker, whose unremarkable life is turned upside-down -- literally -- when he's bitten by a genetically altered spider.