ABC's hit series Ugly Betty will officially start its fourth season on Friday, October 16 with a two-hour premiere at 8pm, and then move to its regular 9pm time slot on Friday, October 23.

The October 16 episode, entitled "The Butterfly Effect," will feature a host of guest stars, including Kristen Johnston, Lynn Redgrave, Judy Gold, Yaya DaCosta, Smith Cho, Rob Bartlett, Alec Mapa, David Rasche, and Ralph Macchio.

The show, which is set in the world of fashion magazines, stars theater veterans America Ferrara, Vanessa Williams, Michael Urie, Ana Ortiz, Tony Plana, Daniel Eric Gold, and Judith Light, along with Eric Mabius, Becki Newton, and Mark Indelicato.