Clarkson's many stage credits include Three Days of Rain, Raised in Captivity, and The Maiden's Prayer. She received an Academy Award nomination for her performance in the movie Pieces of April. Clarkson can currently be seen on the big screen in Friends With Benefits and will appear in the upcoming film Main Street. She won two Emmy Awards for her work on HBO's Six Feet Under.

The series stars Amy Poehler, Rob Lowe, and Nick Offerman.