Sarandon, the only one of the quintet not to have been a series regular, is currently starring on Broadway in Exit the King. Margulies, who played nurse Carol Hathaway for six years, starred on Broadway in Festen.
The Emmy-Award winning series, about life in a hospital emergency room, is currently finishing up its final season, having debuted on NBC in 1994. Other veteran cast members are expected to appear in its remaining episodes.
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